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Epigenetic Aging in Mood Disorders: Exploring the Role of Lithium and Future Therapies

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In this week’s episode of the Everything Epigenetics podcast, Dr. Gabriel Fries and I discuss the fascinating intersections of epigenetics, aging, and psychiatric disorders. Dr. Fries, an Assistant Professor in Psychiatry and Behavioral Sciences at UTHealth, shares his groundbreaking research on the molecular underpinnings of mood disorders such as bipolar disorder and suicide risk. We dive into how psychiatric disorders are linked to accelerated aging, how drugs like lithium show promise in reversing these epigenetic changes, and the future of personalized medicine through pharmacoepigenetics.

In this podcast you’ll learn about:

– The importance of epigenetics in psychiatric disorders
– How psychiatric disorders accelerate the aging process
– The anti-aging effects of lithium in bipolar parents
– How epigenetic markers can help predict treatment responses
– The future of interventional trials aimed at reversing epigenetic aging
– The challenges facing the field and the need for replication studies

Transcript:

About this Guest

Gabriel Fries
Gabriel R. Fries, PhD, is assistant professor in the Faillace Department of Psychiatry and Behavioral Sciences and a translational researcher in the field of biological psychiatry. His research focuses on the epigenetic basis of mood disorders, with a particular interest in bipolar disorder, suicide, and molecular mechanisms of stress.
Everything epigenetic
Everything epigenetic
Epigenetic Aging in Mood Disorders: Exploring the Role of Lithium and Future Therapies
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